Publications

Released by RADIATE

Please find below details of our released publications

Prognostic value, localization and correlation of PD-1/PD-L1, CD8 and FOXP3

Prognostic value, localization and correlation of PD-1/PD-L1, CD8 and FOXP3

Diana A, Wang LM, D’Costa Z, Allen P, Azad A, Silva MA, Soonawall Z, Liu S, McKenna G, Muschel RJ, Fokas E (2016) Prognostic value, localization and correlation of PD-1/PD-L1, CD8 and FOXP3 with the desmoplastic stroma in pancreatic ductal adenocarcinoma. Oncotarget.Advance Online Publication. DOI: 10.18632/oncotarget.10038

Prognostic value, localization and correlation of CA9, CD31, CD68 and CD20

Prognostic value, localization and correlation of CA9, CD31, CD68 and CD20

Diana A, Wang LM D’Costa Z, Azad A, Silva MA, Soonawalla Z, Allen P, Liu S, McKenna G, Muschel RJ, Fokas E (2016) Prognostic value, localization and correlation of CA9, CD31, CD68 and CD20 with the desmoplastic stroma in pancreatic ductal adenocarcinoma. DOI:10.18632/oncotarget.10038

Radiosynthesis and validation of ….

Vincent F. Van Hée, Daniel Labar, Gwenaël Dehon, Debora Grasso, Vincent Grégoire, Giulio G. Muccioli, Raphaël Frédérick, Pierre Sonveaux. Oncotarget. 2017 Jan 17. doi: 10.18632/oncotarget.14705. [Epub ahead of print]. PMID: 28107190

Cancer metabolism in space and time: Beyond the Warburg effect

VPierre Danhier, Piotr Bański, Valéry L Payen, Debora Grasso, Luigi Ippolito, Pierre Sonveaux, Paolo E Porporatoa.. Biochim Biophys Acta. 2017 Feb 4. pii: S0005-2728(17)30023-3. doi: 10.1016/j.bbabio.2017.02.001. [Epub ahead of print]. PMID: 28167100

IL2 based immunotherapies: towards a personalized and curative antitumor response

Nicolle H. Rekers, Veronica Olivo Pimentel, Ala Yaromina, Ludwig Dubois, Philippe Lambin. Vol 5, Supplement 6 (November 2016): Translational Cancer Research. doi: 10.21037/tcr.2016.11.26

Combining radiotherapy with immunotherapy: the past, the present and the future

Van Limbergen EJ, De Ruysscher DK, Olivo Pimentel V, Marcus D, Berbee M, Hoeben A, Rekers N, Theys J, Yaromina A, Dubois LJ, Lambin P. Br J Radiol. 2017 Aug;90(1076):20170157. doi: 10.1259/bjr.20170157. Epub 2017 May 25. Review.

The immunocytokine L19-IL2: An interplay between radiotherapy and long-lasting systemic anti-tumour immune responses

Nicolle H. Rekers, Veronica Olivo Pimentel, Ala Yaromina, Natasja G. Lieuwes, Rianne Biemans, Catharina M. L. Zegers, Wilfred T. V. Germeraad, Evert J. Van Limbergen, Dario Neri, Ludwig J. Dubois & Philippe Lambin (2018) The immunocytokine L19-IL2: An interplay between radiotherapy and long-lasting systemic anti-tumour immune responses, OncoImmunology, 7:4, e1414119,
DOI: 10.1080/2162402X.2017.1414119

Drug Resistance in Non-Small Cell Lung Cancer: A Potential for NOTCH Targeting?

Sosa Iglesias V, Giuranno L, Dubois LJ, Theys J, Vooijs M. Drug Resistance in Non-Small Cell Lung Cancer: A Potential for NOTCH Targeting? Front Oncol. 2018 Jul 24;8:267. doi: 10.3389/fonc.2018.00267. eCollection 2018. Review. PubMed PMID: 30087852; PubMed Central PMCID: PMC6066509

High-throughput Evaluation of Protein Migration and Localization after Laser Micro-Irradiation

Oeck S, Malewicz NM, Krysztofiak A, Turchick A, Jendrossek V, Glazer PM. High-throughput Evaluation of Protein Migration and Localization after Laser Micro-Irradiation. Scientific Reports, 2019, accepted

Restraining Akt1 Phosphorylation Attenuates the Repair of Radiation-Induced DNA Double-Strand Breaks and Reduces the Survival of Irradiated Cancer Cells.

Szymonowicz K., Oeck S., Krysztofiak A., van der Linden J., Iliakis G., Jendrossek V.  Restraining Akt1 Phosphorylation Attenuates the Repair of Radiation-Induced DNA Double-Strand Breaks and Reduces the Survival of Irradiated Cancer Cells. Int J Mol Sci, 2018; 19(8). pii: E2233. DOI: 10.3390/ijms19082233

Relating linear energy transfer to the formation and resolution of DNA repair foci after irradiation with an equal dose of plateau protons, Bragg peak protons or X-ray photons

Oeck S, Szymonowicz K, Wiel G, Krysztofiak A, Lambert J, Koska B, Iliakis G, Timmermann B, Jendrossek V. 2018. Relating linear energy transfer to the formation and resolution of DNA repair foci after irradiation with an equal dose of plateau protons, Bragg peak protons or X-ray photons. International Journal of Molecular Sciences 2018 Nov 28;19(12). pii: E3779. doi: 10.3390/ijms19123779

The Focinator v2-0 – Graphical interface, four channels, colocalization analysis and cell phase identification.

Oeck S., Malewicz N.M., Hurst S., Al-Refae K., Krysztofiak A., Jendrossek V. The Focinator v2-0 – Graphical interface, four channels, colocalization analysis and cell phase identification. Radiation Research, 2017; 188(1):114-120. DOI: 10.1667/RR14746

TERT promoter mutations and polymorphisms as prognostic factors in primary glioblastoma

Mosrati MA, Malmström A, Lysiak M, Krysztofiak A, Hallbeck M, Milos P, Hallbeck AL, Bratthäll C, Strandéus M, Stenmark-Askmalm M, Söderkvist P. TERT promoter mutations and polymorphisms as prognostic factors in primary glioblastoma. Oncotarget. 2015. 6(18): 16663-73 DOI:10.18632/oncotarget.4389

When defense becomes dangerous – transcription factor Nrf2 and cancer

Krysztofiak A, Krajka-Kuźniak V. When defense becomes dangerous – transcription factor Nrf2 and cancer. Advances in Hygiene and Experimental Medicine, 2015. 69: 140-152

Combined Treatment Modalities for High-Energy Proton Irradiation: Exploiting Specific DNA Repair Dependencies

Simon Deycmar and Martin Pruschy (2018) Combined Treatment Modalities for High-Energy Proton Irradiation: Exploiting Specific DNA Repair Dependencies. International Journal of Particle Therapy: Summer 2018, Vol. 5, No. 1, pp. 133-139. https://doi.org/10.14338/IJPT-18-00020.1

Preclinical Evaluation of White Led-Activated Non-porphyrinic Photosensitizer OR141 in 3D Tumor Spheroids and Mouse Skin Lesions

Bastien Doix, Estelle Bastien, Alix Rambaud, Adán Pinto, Caroline Louis, Vincent Grégoire, Olivier Riant and Olivier Feron (2018) Preclinical Evaluation of White Led-Activated Non-porphyrinic Photosensitizer OR141 in 3D Tumor Spheroids and Mouse Skin Lesions. Front. Oncol., 21 September 2018

https://doi.org/10.3389/fonc.2018.00393